Calcium phosphate cement with icariin-loaded gelatin microspheres as a local drug delivery system for bone regeneration.

"Declarations Ethical approval and consent to participateThe research was conducted with the participant’s consent and approved by Medical Ethics Committee of Xi'an Medical University. Consent for publicationAll of the authors agree the article to be published in BioMedical Engineering OnLine. Competing interestsThere are no competing interests in the research. Competing interests There are no competing interests in the research."

"Funding This study was funded by the National Natural Science Foundation of China (No. 81801034), the Youth Talent fund of Xi 'an Association for Science and Technology (No. 095920201328), the Key R&D Program of the Department of Science and Technology of Shaanxi Province (No. 2021SF-028) and the Youth Innovation Team of Shaanxi Universities."