Loss of furin site enhances SARS-CoV-2 spike protein pseudovirus infection.

Authors:
Wang Z; Zhong K; Wang G; Lu Q; Li H and 8 more

Journal:
Gene

Publication Year: 2022

DOI:
10.1016/j.gene.2022.147144

PMCID:
PMC9790109

PMID:
36577450

Journal Information

Full Title: Gene

Abbreviation: Gene

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Molecular Biology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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4/6
66.7% Transparent
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"appendix a supplementary material the following are the supplementary data to this article: supplementary data 1 data availability data will be made available on request."

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"Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."

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"AcknowledgmentsThis study was supported by the National Natural Science Foundation of China (82073404 & 81773188 & 82002648), the Major Subject of the Science and Technology Department of Sichuan Province (2019YFS0110), the 1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University (ZYJC18007) and the special research fund on COVID-19 of West China Hospital Sichuan University (HX-2019-nCoV-064 & HX-2019-nCoV-058). Zeng Wang: Conceptualization, Data curation, Formal analysis, Methodology, Investigation, Writing – original draft. Kunhong Zhong: Data curation, Formal analysis, Methodology, Investigation, Writing – review and editing. Guoqing Wang: Data curation, Formal analysis, Methodology, Investigation, Writing – review and editing. Qizhong Lu: Resources, Data curation, Methodology, Software. Hexian Li: Resources, Data curation, Methodology. Zhiguo Wu: Resources, Data curation, Methodology. Zongliang Zhang: Resources, Data curation, Methodology. Nian Yang: Resources, Data curation, Methodology. Meijun Zheng: Resources, Data curation, Methodology. Yuelong Wang: Funding acquisition. Chunlai Nie: Funding acquisition. Liangxue Zhou: Supervision, Funding acquisition, Writing – review and editing. Aiping Tong: Supervision, Funding acquisition, Writing – review and editing. All authors have read and approved the final manuscript."

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Paper is freely available to read
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Last Updated: Aug 05, 2025