Effect of Cholesterol Content of Lipid Composition in mRNA-LNPs on the Protein Expression in the Injected Site and Liver After Local Administration in Mice.

Authors:
Kawaguchi M; Noda M; Ono A; Kamiya M; Matsumoto M and 4 more

Journal:
J Pharm Sci

Publication Year: 2022

DOI:
10.1016/j.xphs.2022.12.026

PMCID:
PMC9805379

PMID:
36596392

Journal Information

Full Title: J Pharm Sci

Abbreviation: J Pharm Sci

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Pharmacology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
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Evidence found in paper:

"Disclosure Conflicts of Interest The author Shusaku Mizukami has received a research budget from 428 SHIONOGI & CO., LTD. It has been used for the employment of Shusaku Mizukami, but not for 429 other uses in this study Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."

Evidence found in paper:

"Source of Funding This work was partly supported by JSPS KAKENHI Grant Number 21H03818 (S.K.), AMED Grant Number JP22ak0101178 (H.M.)."

Protocol Registration
Open Access
Paper is freely available to read
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Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025