Do Regions of Increased Inflammation Progress to New White Matter Hyperintensities?: A Longitudinal Positron Emission Tomography-Magnetic Resonance Imaging Study.

Authors:
Tozer DJ; Brown RB; Walsh J; Hong YT; Williams GB and 4 more

Journal:
Stroke

Publication Year: 2023

DOI:
10.1161/STROKEAHA.122.039517

PMCID:
PMC9855729

PMID:
36621823

Journal Information

Full Title: Stroke

Abbreviation: Stroke

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Vascular Diseases

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
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Evidence found in paper:

"Disclosures Dr Tozer was funded for this work as both salary and grant support by the Medical Research Council (MRC). Professor O’Brien discloses grants from the MRC, Alliance Medical, Eli Lilley and Company and Merck. He also holds consultancy roles for Biogen, GE Healthcare, Novo Nordisk, Roche and TauRx Therapeutics. Professor Markus discloses grant support from the British Heart Foundation. The other authors report no conflicts."

Evidence found in paper:

"Sources of Funding Recruitment was supported by the National Institute for Health Research Clinical Research Network. The study was funded by a Medical Research Council (MRC) experimental medicine grant (MR/N026896/1). Professor Markus is supported by a National Institute of Health Research (NIHR) Senior Investigator award. This work was supported by infrastructural support from the Cambridge BHF Center of Research Excellence [RE/18/1/34212]. Dr Brown is supported by an Association of British Neurologists Clinical Research Training Fellowship funded by the Guarantors of Brain. The research and Professor O’Brien is supported by the NIHR Cambridge Biomedical Research Center (BRC-1215-20014). The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care."

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Open Access
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Last Updated: Aug 05, 2025