Hypoxia-associated circPRDM4 promotes immune escape via HIF-1α regulation of PD-L1 in hepatocellular carcinoma.

"Declarations Ethics approval and consent to participateEthical approval was obtained from the Ethics Committee of the First Affiliated Hospital of Nanjing Medical University and the Ethics Committee of the First Affiliated Hospital of Wannan Medical College. Informed consent was obtained from all participants. Animal research was conducted in compliance with the Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines and approved by the Institutional Animal Care and Use Committee of Nanjing Medical University (No. 10791) and the Animal Welfare and Ethical Committee of Wannan Medical College (No. LLSC-2020-090). Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding This work was supported by the National Natural Science Foundation of China (82002556, 82103293, 82172651, 81972768, 31930020), the Natural Science Foundation of Jiangsu Province (BK20201083), the Natural Science Foundation of Anhui Province (1908085QH332, 2108085MH287), the Natural Science Foundation of Anhui Education Department for Distinguished Young Scholars (2022AH020074), the Natural Science Foundation of Anhui Education Department for Excellent Young Scholars (2022AH030123), the Support Plan for Outstanding Young Talents of Anhui Education Department (gxyq2021257), the Key Research and Development Project of Anhui Province (202104j07020019), the Science and Technology Project of Wuhu City (2022jc52), the Talent Introduction Science Foundation of Yijishan Hospital, Wannan Medical College (YR202109, YR202110) and the Funding of "Peak" Training Program for Scientific Research of Yijishan Hospital, Wannan Medical College (GF2019J08, GF2019G17)."