Fragility Score: a REMS-based indicator for the prediction of incident fragility fractures at 5 years.

"Declarations Conflict of interestConversano F., Casciaro E. and Casciaro S. owns stocks of Echolight Spa. M.L. Brandi is a scientific advisor at Echolight. All remaining authors have no competing interests to declare that are relevant to the content of the article. Statement of human and animal rightsThe study was approved by the national Ethics Review Board of Azienda Sanitaria Locale (ASL) Lecce (ID: 2258/2011). All procedures were performed in accordance with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Informed consentInformed consent for participation and publication has been obtained from all participants included in the study. Conflict of interest Conversano F., Casciaro E. and Casciaro S. owns stocks of Echolight Spa. M.L. Brandi is a scientific advisor at Echolight. All remaining authors have no competing interests to declare that are relevant to the content of the article."

"Funding Open access funding provided by Consiglio Nazionale Delle Ricerche (CNR) within the CRUI-CARE Agreement."