Multi-organ carcinogenicity by inhalation exposure to 2-Bromopropane in rats.

"DISCLOSURE Approval of the research protocol: The present study was conducted with reference and compliance to the Organisation for the Economic Co‐operation and Development (OECD) Guideline for Testing of Chemicals 451, OECD Principles of Good Laboratory Practices (GLP) and “Standards to be Observed by Testing Institutions” of Ministry of Labour Japan. Informed Consent: N/A. Registry and the Registration No. of the study: Study number of the Japan Bioassay Research Center (JBRC) was 0877. Animal Studies: The rats were cared for in accordance with the Standards relating to the Care and Keeping and Reducing Pain of Laboratory Animals and was reviewed and approved by the Institutional Animal Care and Use Committee of the Japan Bioassay Research Center (JBRC). Approval number was 0144. Conflict of interest statement: The authors declare no conflict of interest. Approval of the research protocol : The present study was conducted with reference and compliance to the Organisation for the Economic Co‐operation and Development (OECD) Guideline for Testing of Chemicals 451, OECD Principles of Good Laboratory Practices (GLP) and “Standards to be Observed by Testing Institutions” of Ministry of Labour Japan. Informed Consent : N/A. Registry and the Registration No. of the study : Study number of the Japan Bioassay Research Center (JBRC) was 0877. Animal Studies : The rats were cared for in accordance with the Standards relating to the Care and Keeping and Reducing Pain of Laboratory Animals and was reviewed and approved by the Institutional Animal Care and Use Committee of the Japan Bioassay Research Center (JBRC). Approval number was 0144. Conflict of interest statement : The authors declare no conflict of interest."

"The present study was contracted and supported by the Ministry of Health, Labour and Welfare, Japan. We wish to express our thanks to Mr. Arata Saito for his help in planning to proceeding, and Dr. David Alexander for valuable advice. We also acknowledge all member of JBRC for their efforts."