Perioperative water and electrolyte balance and water homeostasis regulation in children with acute surgery.

"Competing interests R.T.K. declares that he is employee of Swedish Orphan Biovitrum AB (Sobi™), which had no role in funding, study design, data collection and analysis, decision to publish, or preparation of the manuscript. All other authors declare that there are no relevant financial or nonfinancial competing interests to report."

"Funding Open access funding provided by Karolinska Institute."

"The current study was conducted in Sweden, from 19 May 2021 until 28 February 2022. Ethical approval was given by The Swedish-Ethical Review-Authority (2020–03166). This study protocol was registered at the Australian New Zealand Clinical Trial Registry (https://www.anzctr.org.au ACTRN12621000587808). Before enrollment, all parents provided voluntary written informed consent for their children to participate in this study."