Acute and long-term exercise adaptation of adipose tissue and skeletal muscle in humans: a matched transcriptomics approach after 8-week training-intervention.

"array data were submitted to the geo database at ncbi (gse208032 gse161750 gse161749).; data availability the transcriptomic data used in this study is available via the geo database at ncbi (gse224310). data availability the transcriptomic data used in this study is available via the geo database at ncbi (gse224310"

"Competing interests The authors declare no competing interests."

"Funding This study was supported in part by grants from the German Federal Ministry of Education and Research (BMBF) to the German Centre for Diabetes Research (DZD e.V.; No. 01GI0925) AM is currently funded by a clinician scientist program from the medical faculty of the University of Tübingen. The study was supported by the German Diabetes Society (Allgemeine Projektförderung, 2015, OPR), by the German Center for Diabetes Research (DZD grant 82DZD0019G, OPR), and by the Morgagni Prize of the European Association for the Study of Diabetes 2020 (OPR). Open Access funding enabled and organized by Projekt DEAL."

"Healthy, sedentary (<120 min of physical activity per week) humans at high risk for T2D with at least one of the following risk factors (BMI > 27 kg/m2, family history (first degree) of T2D, former gestational diabetes) were recruited. Out of 25 subjects that were included in the previous data analysis [] a total of 14 subjects were included in the present study due to criteria detailed below. All participants gave written informed consent and the study protocol was approved by the ethics committee of the University of Tübingen and was in accordance with the declaration of Helsinki. The study was registered at Clinicaltrials.gov as trial number NCT03151590."