Inhibition of SUMOylation enhances DNA hypomethylating drug efficacy to reduce outgrowth of hematopoietic malignancies.

"data availability the mass spectrometry proteomics data have been deposited to the proteomexchange consortium via the pride partner repository with the dataset identifiers pxd038617 and pxd038620. the panther overrepresentation test (released 2022-02-02) was used go ontology database doi: 10 5281/zenodo 6399963 released 2022-03-22."

"Competing interests The authors declare no competing interests."

"We are grateful to Prof. A. van den Berg and Dr. J. Kluijver (UMCG, Groningen, the Netherlands) for DLBCL and BL cell lines and to Dr. S.M. Noordermeer (LUMC, Leiden, the Netherlands) for RPE-1 p53-/- and RPE-1 p53-/- BRCA1-/- cell lines. We are grateful to A. de Ru and Dr. P.A. van Veelen for support with the Exploris 480 and to Dr. F. Trulsson for support with analysis of the MS data. This work was funded by the Dutch Cancer Society (grant 10835)."