Knock-out of the critical nitric oxide synthase regulator DDAH1 in mice impacts amphetamine sensitivity and dopamine metabolism.

"Declarations Conflict of interestThe authors declare no conflict of interest. Ethical approval and consent to participateAll animal experiments were carried out in accordance to the European Communities Council Directive of 22nd September 2010 (2010/63/EU) under protocols by the animal ethics committee of the Technische Universität Dresden and the Landesdirektion Sachsen (ID TVV5/2019). All efforts were made to reduce animal suffering and number of animals used. Conflict of interest The authors declare no conflict of interest."

"Funding Open Access funding enabled and organized by Projekt DEAL. This work was funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) grant number GRK2773/1-454245598 and supported by the woman habilitation promotion initiative from the Medical Faculty awarded to N.B. A.A.K. received research scholarships from the German Academic Exchange Service (DAAD) and the Gesellschaft von Freunden und Förderern der TU Dresden. R.R.G. was supported by the project ID: 93018770 of the St. Petersburg State University. The supporting bodies played no role in any aspect of the study design, analysis, interpretation, or decision to publish this data."