Regulon active landscape reveals cell development and functional state changes of human primary osteoblasts in vivo.

"availability of data and materials the scrna-seq data for primary osteoblasts from human sample can be accessed with accession number under gse147390 in geo database. availability of data and materials the scrna-seq data for primary osteoblasts from human sample can be accessed with accession number under gse147390"

"Declarations Ethics approval and consent to participateAll experimental procedures were approved by the Ethics Committee of Xiangya Hospital of Central South University. Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding HMX was partially supported by grants from the National Natural Science Foundation of China (Grant No. 81902277), National Key R&D Program of China (Grant No. 2017YFC1001100)."