Production of rAAV by plasmid transfection induces antiviral and inflammatory responses in suspension HEK293 cells.

Authors:
Chung CH; Murphy CM; Wingate VP; Pavlicek JW; Nakashima R and 4 more

Journal:
Mol Ther Methods Clin Dev

Publication Year: 2023

DOI:
10.1016/j.omtm.2023.01.002

PMCID:
PMC9937832

PMID:
36819978

View on PubMed View on PMC View Publisher
Journal Information

Full Title: Mol Ther Methods Clin Dev

Abbreviation: Mol Ther Methods Clin Dev

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Medicine, Research & Experimental

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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66.7% Transparent
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Evidence found in paper:

"the results and figures generated from dp_gp and goatools python packages can be reproduced using custom python code."

Evidence found in paper:

"Declaration of interests All authors were employed by Pfizer Inc. when the present research was conducted."

Evidence found in paper:

"This project is supported by the Pfizer Worldwide Research, Development, and Medical Postdoctoral training program."

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Last Updated: Aug 05, 2025