Engineering a modular ⁴⁴Ti/⁴⁴Sc generator: eluate evaluation in preclinical models and estimation of human radiation dosimetry.

"Declarations Ethics approval and consent to participateAll applicable international, national, and/or institutional guidelines for the care and use of animals were followed. All radioactive material handling and animal experimentation were conducted in compliance with institutional regulations and approved by Environmental Health and Safety protocol #Thorek 1169-01 and Institutional Animal Care and Use Committee protocol #22-0023, in compliance with ARRIVE guidelines. Consent for publicationNot applicable. Competing interestsThe authors declare no relevant conflicts of interest. Competing interests The authors declare no relevant conflicts of interest."

"Funding This work was supported in part by National Institutes of Health R01CA240711 (DLJT), R01CA229893 (DLJT), R01CA201035 (DLJT), and the Children’s Discovery Institute MC-II-2021–961 (DA). TRIUMF receives federal funding via a contribution agreement with the National Research Council of Canada."