Integrating oculomics with genomics reveals imaging biomarkers for preventive and personalized prediction of arterial aneurysms.

"the data and r code used in this current study are available from the corresponding authors on a reasonable request."

"Declarations Ethics approval and consent to participateThis study was approved by the National Information Governance Board for Health and Social Care and the NHS Northwest Multicentre Research Ethics Committee (11/NW/0382) and the Biobank consortium (application number 62489). Since de-identified data in a public dataset was used, the Medical Research Ethics Committee of Guangdong Provincial People’s Hospital waived the requirements to obtain ethical approval. Consent for publicationNot applicable. Conflict of interestThe authors declare no competing interests. Conflict of interest The authors declare no competing interests."

"Funding Huang Y receives support from the Research Foundation of Medical Science and Technology of Guangdong Province, China (A2022323); NSFC Incubation Project of Guangdong Provincial People’s Hospital, China (KY0120220051); Postdoctoral Research Funds of Guangdong Provincial People’s Hospital (BY012021031); Research Fund for the Postdoctoral Program for NSFC from Provincial People’s Hospital (8210040630) and Science and Technology Program of Guangzhou, China (202002020049); Li C receives support from the National Natural Science Foundation of China (81870663, 82171075), the Outstanding Young Talent Trainee Program of Guangdong Provincial People’s Hospital (KJ012019087), Guangdong Provincial People’s Hospital Scientific Research Funds for Leading Medical Talents and Distinguished Young Scholars in Guangdong Province (KJ012019457) and Talent Introduction Fund of Guangdong Provincial People’s Hospital (Y012018145). He MG receives the High-level Talent Flexible Introduction Fund of Guangdong Provincial People’s Hospital (No. KJ012019530), support from the University of Melbourne at Research Accelerator Program and the CERA Foundation. The Centre for Eye Research Australia receives Operational Infrastructure Support from the Victorian State Government."