The role of brain structure in the association between pubertal timing and depression risk in an early adolescent sample (the ABCD Study®): A registered report.

"all model statistics and mplus outputs for these analyses including single mediator model results (not reported in table 5 ) can be found in the https://osf io/rw3s6/? supplementary data 4 5 we conducted exploratory analyses to identify whether any other brain structural measures (beyond those identified in the pilot analyses) mediated the association between earlier pubertal timing and depressive symptoms."

"all scripts (r and mplus) used in this registered report are available on the github repository for this project: https://github com/niamhmacsweeney/abcd_puberty_depression."

"NM is the recipient of a Mental Health Research UK PhD studentship JA is the recepient of a Wellcome Trust fellowship (grant number: 209176/Z/17/Z). RMR is supported by the 10.13039/501100000274British Heart Foundation (grant number: RE/18/5/34216). This study was also supported by the Wellcome Trust (grant numbers: 220857/Z/20/Z; 104036/Z/14/Z). Biorender.com was used to generate some figures included in this paper. Data used in the preparation of this article were obtained from the Adolescent Brain Cognitive DevelopmentSM (ABCD) Study (https://abcdstudy.org), held in the NIMH Data Archive (NDA). This is a multisite, longitudinal study designed to recruit more than 10,000 children age 9–10 and follow them over 10 years into early adulthood. The ABCD Study® is supported by the 10.13039/100000002National Institutes of Health and additional federal partners under award numbers U01DA041048, U01DA050989, U01DA051016, U01DA041022, U01DA051018, U01DA051037, U01DA050987, U01DA041174, U01DA041106, U01DA041117, U01DA041028, U01DA041134, U01DA050988, U01DA051039, U01DA041156, U01DA041025, U01DA041120, U01DA051038, U01DA041148, U01DA041093, U01DA041089, U24DA041123, U24DA041147. A full list of supporters is available at https://abcdstudy.org/federal-partners.html. A listing of participating sites and a complete listing of the study investigators can be found at https://abcdstudy.org/consortium_members/. ABCD consortium investigators designed and implemented the study and/or provided data but did not necessarily participate in the analysis or writing of this report. This manuscript reflects the views of the authors and may not reflect the opinions or views of the NIH or ABCD consortium investigators. The ABCD data repository grows and changes over time. The NDA DOI for this study is 10.15154/1523126. DOIs can be found at https://nda.nih.gov/general-query.html?q=query=studies%20∼and∼%20dataRepositories=Adolescent%20Brain%20Cognitive%20Development%20∼and∼%20orderBy=id%20∼and∼%20orderDirection=Ascending. NM attended the ABCD Modelling Developmental Change Workshop (grant number: R25MH125545) in July 2021 and would like to extend a special thank you to the organisers (Dr Kate Mills and Dr Michelle Byrne) and participants for their support in the development of this project. CRediT authorship contribution statementNiamh MacSweeney: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing, Project administration. Judith Allardyce: Formal analysis, Methodology, Writing – review & editing. Amelia Edmonston-Stait: Methodology, Writing – review & editing. Xueyi Shen: Data curation, Methodology, Writing – review & editing. Hannah Casey: Methodology, Writing – review & editing. Stella W. Y. Chan: Writing – review & editing, Funding acquisition. Breda Cullen: Methodology, Writing – review & editing. Rebecca M. Reynolds: Methodology, Writing – review & editing. Sophia Frangou: Writing – review & editing. Alex S. F. Kwong: Methodology, Writing – review & editing, Supervision. Stephen M. Lawrie: Methodology, Writing – review & editing, Supervision, Funding acquisition. Liana Romaniuk: Methodology, Writing – review & editing, Supervision. Heather C. Whalley: Conceptualisation, Methodology, Writing – review & editing, Supervision, Funding acquisition."