Structure-based mechanism and inhibition of cholesteryl ester transfer protein.

"these included the cetp-torcetrapib complex (pdb: 4f2a) at 2 6 a resolution [ ] and cetp-compound2 complex (pdb: 4ews) at 3 1 a resolution [ ]."

"Declarations Conflict of InterestThe authors declare that the research was conducted in the absence of any commercial or financial relationships. Human and Animal Rights and Informed ConsentThis article is a review article in the field of lipoproteins. It contains previous publications based on human and animal studies. Conflict of Interest The authors declare that the research was conducted in the absence of any commercial or financial relationships."

"Funding This work at the molecular foundry, Lawrence Berkeley National Laboratory was supported by the Office of Science, Office of Basic Energy Sciences of the United States Department of Energy (contract no. DE-AC02-05CH11231), US National Institutes of Health grants R01HL115153, R01GM104427, R01MH077303, R01DK042667 (GR, HX, JL, MZ). The work was supported by the Beijing National Laboratory for Molecular Science, National Key R&D Program of China (Nos. 2020YFE0100300 and 2018YFA0208502) and Key Research Program of Frontier Sciences, CAS, grant No. ZDBSLYSLH031 (JW). HX was partially funded from JW."