p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma.

"Declarations Ethics approval and consent to participateThis study was approved by the Ethics Committee of Peking University Third Hospital (S2021251), and all the participants signed informed consent. The animal experiment was approved by the Laboratory Animal Welfare Ethics Committee of Peking University Health Science Center (LA2016029). Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding This study was supported by: Beijing Medical and Health Foundation (YWJKJJHKYJJ-B20081FN, Grant to Hongmei Jing); Special Fund for Clinical Research of Wu Jieping Medical Foundation (320.6750.2021-04-24, Grant to Hongmei Jing); Queue Construction Project of Peking University Third Hospital (BYSYDL2021006, Grant to Hongmei Jing); and Beijing Natural Science Foundation(7232202, Grant to Hongmei Jing)."