Overexpression of Lmo2 initiates T-lymphoblastic leukemia via impaired thymocyte competition.

"data availability rna-seq data are available in ncbi gene expression omnibus (accession gse188225 ) and exome sequencing data are available in ncbi bioproject (accession prjna909315). data availability rna-seq data are available in ncbi gene expression omnibus (accession gse188225"

"Disclosures: The Walter and Eliza Hall Institute receives milestone and royalty payments related to Venetoclax, and employees may also be eligible for benefits related to these payments. W.S. Alexander and I.J. Majewski reported receiving payments from the Walter and Eliza Hall Institute related to Venetoclax. M.P. McCormack is an employee of iCamuno Biotherapeutics and has served as a consultant for AstraZeneca. D.H.D. Gray reported “other” from Walter and Eliza Hall Institute and grants from Servier outside the submitted work. X. Liu is co-founder of iCamuno Biotherapeutics. No other disclosures were reported."

"This work was supported by an Alan W. Harris Scholarship and an Australian Postgraduate Award (to H.D. Abdulla) from the Australian Government, project grants (1003391 to M.P. McCormack, 1187367 to D.H.D. Gray, and 1104145 to M.P. McCormack and I.J. Majewski), a Program grant (1113577 to W.S. Alexander), Fellowships (1154970 to G.K. Smyth, 1158024 to D.H.D. Gray, and 1058344 to W.S. Alexander), and the Independent Research Institute’s Infrastructure Support Scheme from the National Health and Medical Research Council of Australia, a grant-in-aid from the Cancer Council of Victoria, a Future Fellowship from the Australian Research Council (to M.P. McCormack), and a Victorian State Government Operational Infrastructure Support grant."