Burden of disease among patients with prevalent Crohn's disease: results from a large German sickness fund.

"Declarations Ethics approvalDue to the non-interventional, retrospective study design using fully anonymized data, ethics approval was not required for this study. Consent to participateDue to the non-interventional, retrospective study design using fully anonymized data, informed consent was not required for this study. Consent for publicationNot applicable. Conflict of interestEZ and BAF are employees of Cytel. The work of Cytel was sponsored by Janssen-Cilag. AB, RN, IB, JNB, JL, AP, and DW are employees of Janssen-Cilag. UM is an employee of AOK PLUS and declares no conflicts of interest. BB has received consulting fees from Abbvie, MSD, Shire, Ferring, UCB, Hospira, Takeda, Movetis, Shield Therapeutics, Pfizer, Biogen, Janssen, Hexal, Cellgene, Boehringer, Allergan, Galapagos, and Arena; provided speeches/lectures for Abbvie, Ferring, MSD, Merckle, Falk, HLR, UCB, Shield Therapeutics, Pfizer, Celltrion, Takeda, Janssen, Mundipharma, and Arena; and received research grants from Abbvie, Ferring, UCB, Given Imaging, Janssen, Takeda, Pfizer, and Galapagos. TW is a staff member of IPAM e.V. and has received honoraria from several pharmaceutical/consultancy firms, e.g., Novo Nordisk, Abbvie, Merck, GSK, BMS, LEOPharma, Bayer, Boehringer Ingelheim. MG is an employee of Cytel and staff member of IPAM e.V. Conflict of interest EZ and BAF are employees of Cytel. The work of Cytel was sponsored by Janssen-Cilag. AB, RN, IB, JNB, JL, AP, and DW are employees of Janssen-Cilag. UM is an employee of AOK PLUS and declares no conflicts of interest. BB has received consulting fees from Abbvie, MSD, Shire, Ferring, UCB, Hospira, Takeda, Movetis, Shield Therapeutics, Pfizer, Biogen, Janssen, Hexal, Cellgene, Boehringer, Allergan, Galapagos, and Arena; provided speeches/lectures for Abbvie, Ferring, MSD, Merckle, Falk, HLR, UCB, Shield Therapeutics, Pfizer, Celltrion, Takeda, Janssen, Mundipharma, and Arena; and received research grants from Abbvie, Ferring, UCB, Given Imaging, Janssen, Takeda, Pfizer, and Galapagos. TW is a staff member of IPAM e.V. and has received honoraria from several pharmaceutical/consultancy firms, e.g., Novo Nordisk, Abbvie, Merck, GSK, BMS, LEOPharma, Bayer, Boehringer Ingelheim. MG is an employee of Cytel and staff member of IPAM e.V."

"Funding This work was funded by Janssen-Cilag."