TREM2 gene expression associations with Alzheimer's disease neuropathology are region-specific: implications for cortical versus subcortical microglia.

"Declarations Conflict of interestTH is a member of the scientific advisory board for Vivid Genomics (outside the work presented herein). No other authors report any relevant conflicts. Ethical approval and consent to participateAll protocols were conducted with approval by the Rush University Medical Center Institutional Review Board after written informed consent from all participants was obtained which included the Anatomical Gift Act. These secondary analyses were approved by the Vanderbilt University Medical Center Institutional Review Board. Consent for publicationAll authors have given consent to the publication of this manuscript. Conflict of interest TH is a member of the scientific advisory board for Vivid Genomics (outside the work presented herein). No other authors report any relevant conflicts."

"This research was supported in part by RO1-AG059716, K01-AG049164, R21-AG059941, R01-AG061518, Alzheimer’s Association IIRG-08-88733, T32 AG058524, and the Vanderbilt Memory & Alzheimer’s Center. ROSMAP is supported by P30AG10161, P30AG72975, R01AG15819, R01AG17917. U01AG46152, U01AG61356."