Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes.

"data availability all available data are incorporated into this article and its online supplementary material imature and myokit are both freely available and can be downloaded from the authors' websites ( www github com/jordiheijman and http://www myokit org )."

"the model code is freely accessible at www github com/jordiheijman .; data availability all available data are incorporated into this article and its online supplementary material imature and myokit are both freely available and can be downloaded from the authors' websites ( www github com/jordiheijman and http://www myokit org ). data availability all available data are incorporated into this article and its online supplementary material imature and myokit are both freely available and can be downloaded from the authors' websites ( www github com/jordiheijman and http://www myokit org )."

"Declarations Conflict of interestMarkus Rapedius is an employee of Nanion Technologies GmbH. The authors have no further conflicts of interest to declare. Ethical approvalThis study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of University Medical Center Göttingen (10/9/15). Conflict of interest Markus Rapedius is an employee of Nanion Technologies GmbH. The authors have no further conflicts of interest to declare."

"Funding Open Access funding enabled and organized by Projekt DEAL. This work was supported by grants from the Deutsche Forschungsgemeinschaft (DFG) to NV (VO 1568/3-1, VO1568/4-1, IRTG1816, SFB1002 project A13 and under Germany’s Excellence Strategy—EXC 2067/1—390729940), from the Else-Kröner-Fresenius Foundation to NV (EKFS 2016_A20) and KSB and SS (EKFS 2017_A137), from the German Center for Cardiovascular Research to NV (DZHK 81X4300102, 81X4300115, 81X4300112), and by the Netherlands Organization for Scientific Research to JH (NWO/ZonMW Vidi 09150171910029)."