TIGIT mediates activation-induced cell death of ILC2s during chronic airway allergy.

"data availability the presented data sets can be found in the gene expression omnibus under accession no gse212180"

"Disclosures: The authors declare no competing interests exist."

"This work was supported in part by the Grants-in-Aid for Scientific Research Program of the Japanese Society for the Promotion of Science (grant numbers 21H02707 and 21K19368 to T. Ebihara, 20H03832 to T. Yamada, and 23K08954 to T. Yamada), the Takeda Science Foundation (to T. Ebihara), the Terumo Life Science Foundation (to T. Ebihara), the Naito Foundation (to T. Ebihara), the Cooperative Research Project Program of the Medical Institute of Bioregulation, Kyushu University (to T. Ebihara), the Novartis Foundation (to T. Ebihara), the Daiichi Sankyo Foundation of Life Science (to T. Ebihara), and the Koyanagi Foundation (to T. Ebihara). Open Access funding provided by Akita University. Author contributions: Conceptualization: T. Ebihara; Methodology: T. Yamada, M. Tatematsu, S. Takasuga, A. Fuchimukai, K. Yamagata, S. Seki, K. Kuba, H. Yoshida, I. Taniuchi, G. Bernhardt, K. Shibuya, A. Shibuya, T. Yamada, and T. Ebihara; Funding acquisition: T. Ebihara, T. Yamada, and T. Yamada; Writing: all authors."