Natural selection differences detected in key protein domains between non-pathogenic and pathogenic feline coronavirus phenotypes.

"we generated codon-aware alignments for each filtered set of protein sequences following the procedure available at the github repository codon-msa (github com/veg/hyphy-analyses/tree/master/codon-msa)."

"Conflict of interest: None declared."

"Funding This study received funding (FOA PAR-18-604) from the US Food and Drug Administration’s Veterinary Laboratory Investigation and Response Network under grant 1U18FD006993-01, awarded to L.B.G. and M.J.S. G.W. is supported by the Michael Zemsky Fund for Feline Disease and the Feline Health Center at the College of Veterinary Medicine, Cornell University. A.C. is supported by T32EB023860 from the National Institute of Biomedical and Bioengineering. Support for this study was provided in part by grants R01 AI134384 (NIH/NIAID) and R01 AI134384 (NIH/NIAID)."