Extracellular vesicles from immortalized mesenchymal stromal cells protect against neonatal hypoxic-ischemic brain injury.

"Declarations Ethics approval and consent to participateHuman MSCs were raised from bone marrow samples of healthy donors after informed consent according to the Declaration of Helsinki, as described previously (6). Animal experiments were performed in accordance to the Animal Research Reporting of in Vivo Experiments (ARRIVE) guidelines with government approval by the State Agency for Nature, Environment and Consumer Protection North Rhine-Westphalia. Consent for publicationNot applicable. Competing interestsBG is a Scientific Advisory Board Member of Innovex Therapeutics SL and Mursla Ltd., a consultant of Fujifilm, and a founding director of Exosla Ltd. The other authors declare that they have no competing interests. Competing interests BG is a Scientific Advisory Board Member of Innovex Therapeutics SL and Mursla Ltd., a consultant of Fujifilm, and a founding director of Exosla Ltd. The other authors declare that they have no competing interests."

"Funding Open Access funding enabled and organized by Projekt DEAL. This work was supported by a research grant from the European Society for Paediatric Research (ESPR) provided to N. L., the Else-Kröner-Fresenius-Stiftung (2018_A113) provided to J. H., and the European Union (European Regional Development Fund 2014–2020 and ERA-NET EuroTransBio 11 EVTrust [031B0332B]) provided to B. G."