Efficacy and safety of Ixekizumab vs. low-dose IL-2 vs. Colchicine vs. standard of care in the treatment of patients hospitalized with moderate-to-critical COVID-19: A pilot randomized clinical trial (STRUCK: Survival Trial Using Cytokine Inhibitors).

Journal Information

Full Title: Rev Soc Bras Med Trop

Abbreviation: Rev Soc Bras Med Trop

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Tropical Medicine

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
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Evidence found in paper:

"Conflicts of Interest: None of the authors have any conflicts of interest or financial ties to disclose."

Evidence found in paper:

"Financial Support: This study was fully funded by the Brazilian governmental agency, the National Council for Scientific and Technological Development (CNPq Brazil), in partnership with the Ministry of Science, Technology, and Innovation (Rede Vírus MCTI), Process no. 402422/2020-1, and 309098/2020-3."

Evidence found in paper:

"The STRUCK trial was conducted in accordance with ethical principles of human experimentation and with the Declaration of Helsinki revised in 2000. All sites received approval from the Institutional Review Board (CAAE 37880620.0.1001.5440), and the study was registered at ClinicalTrials.gov (NCT04724629). All patients or their legal representatives signed an informed consent form before the study procedure."

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Paper is freely available to read
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Last Updated: Aug 05, 2025