Secretory MPP3 reinforce myeloid differentiation trajectory and amplify myeloid cell production.

Authors:
Kang YA; Paik H; Zhang SY; Chen JJ; Olson OC and 6 more

Journal:
J Exp Med

Publication Year: 2023

DOI:
10.1084/jem.20230088

PMCID:
PMC10140385

PMID:
37115584

Journal Information

Full Title: J Exp Med

Abbreviation: J Exp Med

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Allergy and Immunology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
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Evidence found in paper:

"data availability rna-seq data have been deposited in the gene expression omnibus under accession code gse181902 . data availability rna-seq data have been deposited in the gene expression omnibus under accession code gse181902"

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Evidence found in paper:

"Disclosures: J.J. Chen reported personal fees from Yale University and IsoPlexis during the conduct of the study, and personal fees from IsoPlexis and PhenomeX outside the submitted work; in addition, J.J. Chen had a patent number 10274486 with royalties paid (Yale University). R. Fan reported “other” from IsoPlexis, Singleron Biotechnologies, and AtlasXomics outside the submitted work; in addition, R. Fan had a patent to US Patent App. 17/204,279 licensed (IsoPlexis), a patent to US Patent 10,983,116 licensed (IsoPlexis), and a patent to US Patent 10,274,486 licensed (IsoPlexis). R. Fan is a scientific co-founder and advisor for IsoPlexis, Singleron Biotechnologies, and AtlasXomics with a financial interest. No other disclosures were reported."

Evidence found in paper:

"Y-A. Kang was supported by a postdoctoral research award from UCSF Program for Breakthrough Biomedical Research, a Leukemia and Lymphoma Society (LLS) Special Fellowship, and National Institutes of Health (NIH) grant K01 DK120780; H. Paik by the Health Industry Development Institute (KHIDI HI22C1318), the Ministry of Science and ICT of Korea (N-23-NM-CA01-S01), and Korea Institute of Science and Technology Information (KISTI K-23-L02-C04-S01); O. Olson by CRI/Margaret Dammann Eisner postdoctoral fellowship CRI3617; C. Mitchell by NIH grant F31HL160207 and a NYSTEM training grant, A. Collins by NIH grant K08 DK124657 and a Louis V. Gerstner Jr. Scholar Award, J. Swann by a long-term EMBO postdoctoral fellowship ALTF-2021-196, and M. Warr by an LLS Special Fellowship. This work was supported by NIH grants R01 HL092471 and R35 HL135763 grants, LLS Scholar Award to E. Passegué, and the NIH Cancer Center Support Grant P30 CA013696 to CUIMC. The funders of this work had no role in study design, data collection and analysis, the decision to publish, or in the preparation of the manuscript."

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Open Access
Paper is freely available to read
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Last Updated: Aug 05, 2025