Differences in transcriptional changes in psoriasis and psoriatic arthritis skin with immunoglobulin gene enrichment in psoriatic arthritis.

"bulk transcriptomic data from the biopsies of 16 participants with psoriasis without psa in the publicly available dataset gse121212 were downloaded from the gene expression omnibus database together with data for 16 age- and gender-matched hc samples from the same study [ ].; data availability data analysed during the current study are available in the gene expression omnibus (geo) repository under accession gse205748; https://www ncbi nlm nih gov/geo/query/acc cgi? deseq2 v1 24 was used to normalize the read counts and perform pairwise differential expression (pde) analysis between hc and uninvolved skin and hc and lesional skin ( supplementary data s1 available at rheumatology online). data availability data analysed during the current study are available in the gene expression omnibus (geo) repository under accession gse205748"

"Disclosure statement : The authors have declared no conflicts of interest."

"Funding This project was funded by a Chief Scientists Office Clinical Academic Fellowship (CAF16/06) and a private donation. Work in I.B.M.’s and S.S.’s groups is supported by Research into Inflammatory Arthritis Centre Versus Arthritis (RACE) [grant number 22072]. Work in G.G.’s lab is funded by Medical Research Council [MR/M019764/1] and the Wellcome Trust [217093/Z/19/Z]. Disclosure statement: The authors have declared no conflicts of interest."