Elimination of methicillin-resistant Staphylococcus aureus biofilms on titanium implants via photothermally-triggered nitric oxide and immunotherapy for enhanced osseointegration.

"Declarations Ethics approval and consent to participateAll in vivo animal experiments were conducted according to the institutional guidelines and relevant regulations for Animal Experimentation of Laboratory Animals of Chongqing Medical University and the Seventh Medical Center of PLA General Hospital, and approved by the Animal Ethics Committees of the Chongqing Medical University (2021-738) and the Seventh Medical Center of PLA General Hospital (2021-110). Consent for publicationNot applicable. Competing interestsThe authors declare no competing financial interest. Competing interests The authors declare no competing financial interest."

"Funding This work was financially supported by the National Natural Science Foundation of China (82101069, 82102537, 82160411, 82002278), the Natural Science Foundation of Chongqing Science and Technology Commission (CSTC2021JCYJ-MSXMX0170, CSTB2022BSXM-JCX0039), the First Affiliated Hospital of Chongqing Medical University Cultivating Fund (PYJJ2021-02), the Beijing Municipal Science & Technology Commission (Z221100007422130), and the Youth Incubation Program of Medical Science and Technology of PLA (21QNPY116)."