Cortico-muscular coherence in primary lateral sclerosis reveals abnormal cortical engagement during motor function beyond primary motor areas.

"Conflict of interest statement Prof. Hardiman’s work is funded by the Science Foundation Ireland (Grants 20/SP/8953, 16/RC/3948, and 16/ERCD/3854), Health Research Board, and Thierry Latran Foundation. She has served on advisory boards for the following companies: Cytokinetics, Wave Pharmaceuticals, Orion, Novartis, Biogen Denali, Neurosense, Pfizer, Sanofi, and Lilly. She is a member of the DSMC for Accelsior. She is a principal investigator on the PRECISION ALS Project and the Academic/Industry Collaboration funded by Science Foundation Ireland. Her industry partners include Biogen, Takeda, Cytokinetics, Novartis IQVIA, and Accenture. Her research group has collaborated with Biogen, Ionis, and Cytokinetics in delivering the IMPACT ALS Survey and with Cytokinetics in delivering the REVEALS study of respiratory decline in ALS. She is the editor in chief of the Journal ALS and the Frontotemporal Degenerations and is a member of the editorial board of the Journal of Neurology, Neurosurgery and Psychiatry. Prof. Richard Carson is a Senior Editor of the Journal of Physiology and an Associate Editor of Human Movement Science. Other authors declare no conflict of interest."

"Funding This work was supported by Irish Research Council (GOIPD/2015/213, GOIPG/2019/748, and EPSPD/2020/108); the Health Research Board of Ireland (MRCG-2018-02); Science Foundation Ireland (16/ERCD/3854); Research Motor Neurone (MRCG-2018-02); Royal Society-Science Foundation Ireland (URF\R1\221917); Motor Neurone Disease Association (McManus/Apr22/888-791); and ALS Association (20-IIA-546)."