Early Detection of Brain Metastases in a Supervised Exercise Program for Patients with Advanced Breast Cancer: A Case Report.

"Competing Interests: K. S. has received speaker honorarium from Adviva, Germany. The rest of authors declare that they have no competing interests."

"Statements and declarations: The EFFECT study is part of the PREFERABLE project and has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No 825677. The study is also funded by the National Health and Medical Research Council of Australia (2018/GNT1170698). These funding bodies do not have any role during the execution, analyses, interpretation of the data, or decision to submit the results of this study. To conclude, our case report supports the advantages of implementing physical exercise programs that are supervised by qualified professionals as part of routine cancer care for patients in need. This may not only lead to physical and psychological improvements but may also contribute to better patient outcomes through follow-up. We recommend close collaboration between the medical team and exercise professionals because of their unique positioning and skill set to detect subtle deteriorations in health early."