Management of Suspected Life-Threatening Perioperative Anaphylaxis and Risk Factors for Near-Fatal and Fatal Outcomes: A Retrospective Study in China.

"Disclosure The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article."

"The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the Scientific Research Fund of China-Japan Friendship Hospital (No. 2017-RC-3)."

"We conducted a retrospective analysis of data from the nationwide suspected life-threatening POA database that was established by us for our previous epidemiological study. The reference period for the present study was from September 2018 to August 2019. This database includes written and electronic case report forms and anesthesia record forms from 112 tertiary hospitals in mainland China. The study was approved by the Institutional Review Board of China-Japan Friendship Hospital and registered at the Chinese Clinical Trials Registry on September 15, 2019 (ChiCTR1900025956). The requirement for informed consent in the retrospective study was waived by Institutional Review Board of China-Japan Friendship Hospital. All data in the case report forms and anesthesia record forms for this retrospective study are anonymous, and therefore informed consent was unnecessary. The study was conducted in compliance with the Declaration of Helsinki and funded by National Centre for Medical Service Administration, National Health and Family Planning Commission, China (Bureau of Medical Administration [2019] No. 049). STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) checklist for cross-sectional studies was followed for the conduct and reporting of this study. Ethics Approval: The study was approved by the Institutional Review Board of China-Japan Friendship Hospital and registered at the Chinese Clinical Trials Registry on September 15, 2019 (ChiCTR1900025956). The study was conducted in compliance with the Declaration of Helsinki and funded by National Centre for Medical Service Administration, National Health and Family Planning Commission, China (Bureau of Medical Administration [2019] No. 049)."