Non-invasive treatment of ischemia/reperfusion injury: Effective transmission of therapeutic near-infrared light into the human brain through soft skin-conforming silicone waveguides.

"CONFLICT OF INTEREST Maik Hüttemann and Thomas H. Sanderson are co‐founders of Mitovation, Inc. that develops IRL therapy for ischemia/reperfusion injury applications. Samuel Tuck served as systems engineer and Tom Waddell serves as COO of Mitovation, Inc. All other authors declare no potential conflict of interest."

"This work was supported by U.S. National Institutes of Health STTR grant R42NS105238, U44NS125160, and R01NS120322. The laser system was developed through the Peer Reviewed Medical Research Program Award No. W81XWH‐16‐1‐0175 of the Office of the Assistant Secretary of Defense for Health Affairs. Opinions, interpretations, conclusions, and recommendations are those of the authors and are not necessarily endorsed by the funding agencies including the Department of Defense or the National Institutes of Health. We thank Ms. Barbara Rosso‐Norgan at Wayne State University and the Wayne State University School of Medicine Body Bequest Program and anonymous donors for providing human cadavers, and the Lumitex team (Strongsville, OH) for the laser system."