Lung cancer lesion detection in histopathology images using graph-based sparse PCA network.

"Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Dr. Charles Hatt is employed by and has stock options in Imbio, Inc. Dr. Craig Galban is co-inventor of Parametric Response Mapping, which the University of Michigan has licensed to Imbio, Inc., and has a financial interest in Imbio, Inc."

"Sundaresh Ram: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing. Wenfei Tang: Formal analysis, Methodology, Software, Validation, Writing – review & editing. Alexander J. Bell: Data curation, Project administration, Validation, Visualization, Writing – review & editing. Ravi Pal: Data curation, Validation, Visualization, Writing – review & editing. Cara Spencer: Data curation, Writing – review & editing. Alexander Buschhaus: Data curation, Writing – review & editing. Charles R. Hatt: Formal analysis, Investigation, Project administration, Supervision, Writing – review & editing. Marina Pasca diMagliano: Resources, Supervision, Writing – review & editing. Alnawaz Rehemtulla: Project administration, Supervision, Writing – review & editing. Jeffrey J. Rodríguez: Conceptualization, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing. Stefanie Galban: Data curation, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing. Craig J. Galban: Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Validation, Visualization, Writing – review & editing. ☆: This work was supported in part by the 10.13039/100000050National Heart, Lung, and Blood Institute of the National Institute of Health under Grant R01HL139690 and in part by grant support awarded to Dr. Stefanie Galban by the Rogel Cancer Center at the University of Michigan."