Production and characterization of an AAV1-VP3-only capsid: An analytical benchmark standard.

"the aav1-m211v-vp3 cryo-em reconstructed density map and model built for the capsid were deposited in the electron microscopy databank with the accession numbers emd: 29377 and pdb: 8fq4 .; mass spectrometry-related data are available through the public depository massive: massive msv000091640 ftp://massive ucsd edu/msv000091640/ ."

"Declaration of interests W.L., K.M., S.B., and R.V. are employees of Thermo Fisher Scientific."

"We thank the UF-ICBR Electron Microscopy Core for the access to electron microscopes utilized for negative stain electron microscopy and cryo-EM screening. The TF20 cryo-electron microscope was provided by the UF College of Medicine (COM) and Division of Sponsored Programs (DSP). Data collection at Florida State University was made possible by NIH grants S10 OD018142-01 Purchase of a direct electron camera for the Titan-Krios at FSU (PI Taylor) and S10 RR025080-01 Purchase of a FEI Titan Krios for 3-D EM (PI Taylor). The University of Florida COM, NIH GM082946 (PI R McKenna), provided partial funds for the research. 10.13039/100011033Thermo Fisher Scientific provided funds for this study (AGR00021385 and AGR00023336)."