Efficacy of image-enhanced endoscopy for colorectal adenoma detection: A multicenter, randomized trial.

"Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article."

"Supported by the National Key R&D Program of China, No. 2018YFC1315005; National Natural Science Foundation of China, No. 82002515; Shanghai Sailing Program, No. 20YF1407200; and China Postdoctoral Science Foundation, No. 2020M681177."

"Trail design: This prospective, multicenter, randomized, controlled trial was conducted at 4 hospitals in China in following the ethical principles of Declaration of Helsinki (B2019-131R). The study was prepared following the Consolidated Standards of Reporting Trials statement for reporting randomized controlled trials (RCTs)[], and was registered on the Chinese Clinical Trial Registry (ChiCTR1900026026). This was a nonprofit study, and no funding was received or solicited from endoscopy equipment manufacturers. All authors had access to the study data and have reviewed and approved the final manuscript. The full trial protocol see supplement. Clinical trial registration statement: This study was registered on the Chinese Clinical Trial Registry (ChiCTR1900026026)."