Establishing normative data for the evaluation of cognitive performance in Huntington's disease considering the impact of gender, age, language, and education.

"Declarations Conflicts of interestA.M, K.L., R.H., J.K., G.B.L: their institutions have received compensation for clinical trial services from the following companies: Hoffmann-La Roche, Novartis, Prilenia, Wave and the CHDI Foundation Non-financial support (travel and accommodation reimbursement) from European Huntington’s Disease Network. W.F, M.W., O.B, O.K.; J.M.: nothing to disclose. Ethical standard statementThis study was based on the anonymous data set extracted from the periodic data set 4 (PDS4) of the Enroll-HD study. Enroll-HD was approved by the local institutional ethical review boards at every study site and conducted in accordance with the ethical standards described in the Declaration of Helsinki of 1964. All participants provided written informed consent for their participation. Conflicts of interest A.M, K.L., R.H., J.K., G.B.L: their institutions have received compensation for clinical trial services from the following companies: Hoffmann-La Roche, Novartis, Prilenia, Wave and the CHDI Foundation Non-financial support (travel and accommodation reimbursement) from European Huntington’s Disease Network. W.F, M.W., O.B, O.K.; J.M.: nothing to disclose."

"Funding Open Access funding enabled and organized by Projekt DEAL. This work was supported by the Neurology department at Ulm University, Germany, by the Joint Program-Neurodegenerative Disease Research (JPND) project number 8F19004, by the Charles University grant PROGRES Q27/LF1 and by the European Reference Network for Rare Neurological Diseases-Project ID No 739510."