A systematic review of environmental factors related to WNV circulation in European and Mediterranean countries.

"data availability no data was used for the research described in the article. appendix a supplementary data to this article can be found online at https://doi"

"Declaration of Competing Interest None."

"Funding This research was supported by CIBER -Consorcio Centro de Investigación Biomédica en Red-, 10.13039/501100004587Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación and Unión Europea. ESP22PI05 and 10.13039/501100000780EU grant 874850 MOOD and is catalogued as MOOD 000. The contents of this publication are the sole responsibility of the authors and don't necessarily reflect the views of the European Commission."

"A systematic review was performed between June 1st, 2021, and June 30th, 2021 on the influence of environmental factors and their changes on WNV presence, dynamics and epidemiology in EU and MR in the last two decades following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines for systematic reviews and meta-analyses []. The study protocol was registered in the PROSPERO (https://www.crd.york.ac.uk/PROSPERO/) and was accepted on May 16th, 2021 (PROSPERO ID CRD42021235292). To evaluate internal and external validity of the selected publications, a 12-items quality assessment tool was used and adapted (supplementary table 1). Quality was scored as a binary variable (yes/no) and the sum of 1 (“yes”?) gave the final evaluation. The complete search strategy and quality assessment are detailed in supplemental material 1."