"Heads Up" for Creatine Supplementation and its Potential Applications for Brain Health and Function.

"Declarations FundingThis article is based on a presentation by Darren G. Candow to the GSSI Expert Panel in October 2022. Funding for participation in that meeting together with an honorarium for preparation of this article were provided by the GSSI. No other sources of funding were used to assist in the preparation of this article. Conflict of InterestDGC has conducted industry-sponsored research involving creatine supplementation and received creatine donations for scientific studies and travel support for presentations involving creatine supplementation at scientific conferences. In addition, DGC serves on the Scientific Advisory Board for Alzchem (a company that manufactures creatine) and as an expert witness/consultant in legal cases involving creatine supplementation. SCF has previously served as a scientific advisor for a company that sold creatine monohydrate and has received industry-sponsored research involving creatine supplementation and received creatine donations for scientific studies. SMO serves on the Scientific Advisory Board for Alzchem (a company that manufactures creatine). SMO owns patent “Sports Supplements Based on Liquid Creatine” at European Patent Office (WO2019150323 A1), and active patent application “Synergistic Creatine” at UK Intellectual Property Office (GB2012773.4). SMO has served as a speaker at Abbott Nutrition, a consultant of Allied Beverages Adriatic and IMLEK, and has received research funding related to creatine from the Serbian Ministry of Education, Science, and Technological Development, Provincial Secretariat for Higher Education and Scientific Research, AlzChem GmbH, KW Pfannenschmidt GmbH, ThermoLife International LLC, and Hueston Hennigan LLP. SMO does not own stocks and shares in any organization. All other authors have no conflicts of interest that are directly relevant to the content of this article. Ethics Approval Not applicable. Consent to Participate Not applicable. Consent for Publication Not applicable. Availability of Data and Material Not applicable. Code AvailabilityNot applicable. Author ContributionsDGC developed the paper concept and idea. All authors assisted with primary writing. All authors have read and approved the final manuscript. Conflict of Interest DGC has conducted industry-sponsored research involving creatine supplementation and received creatine donations for scientific studies and travel support for presentations involving creatine supplementation at scientific conferences. In addition, DGC serves on the Scientific Advisory Board for Alzchem (a company that manufactures creatine) and as an expert witness/consultant in legal cases involving creatine supplementation. SCF has previously served as a scientific advisor for a company that sold creatine monohydrate and has received industry-sponsored research involving creatine supplementation and received creatine donations for scientific studies. SMO serves on the Scientific Advisory Board for Alzchem (a company that manufactures creatine). SMO owns patent “Sports Supplements Based on Liquid Creatine” at European Patent Office (WO2019150323 A1), and active patent application “Synergistic Creatine” at UK Intellectual Property Office (GB2012773.4). SMO has served as a speaker at Abbott Nutrition, a consultant of Allied Beverages Adriatic and IMLEK, and has received research funding related to creatine from the Serbian Ministry of Education, Science, and Technological Development, Provincial Secretariat for Higher Education and Scientific Research, AlzChem GmbH, KW Pfannenschmidt GmbH, ThermoLife International LLC, and Hueston Hennigan LLP. SMO does not own stocks and shares in any organization. All other authors have no conflicts of interest that are directly relevant to the content of this article."

"Funding This article is based on a presentation by Darren G. Candow to the GSSI Expert Panel in October 2022. Funding for participation in that meeting together with an honorarium for preparation of this article were provided by the GSSI. No other sources of funding were used to assist in the preparation of this article."