Chromatin accessibility uncovers KRAS-driven FOSL2 promoting pancreatic ductal adenocarcinoma progression through up-regulation of CCL28.

"we obtained available scrna-seq data of pdac samples from the genome sequence archive under project prjca001063 and accession number cra001160 ( https://ngdc cncb ac cn/search/?; the accession numbers for the bulk atac-seq h3k27ac chip-seq rna-seq and fosl2 cut&tag reported in this paper are gse190900 gse190901 gse190903 and gse190912 respectively. data availability the sequencing data were uploaded to geo. the accession numbers for the bulk atac-seq h3k27ac chip-seq rna-seq and fosl2 cut&tag reported in this paper are gse190900"

"Competing interests The authors declare no competing interests."

"Funding This research was supported by the Key Research and Development Program of Shandong Province (2021ZLGX02), Taishan Scholars Climbing Program of Shandong Province (tspd20210323), and Tumour Biomarker Innovation Team Foundation of Jinan City (2019GXRC004, 2021GXRC020)."