Molecular networking identifies an AHR-modulating benzothiazole from white button mushrooms (<i>Agaricus bisporus</i>).

"Declaration of Competing Interest: The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Joshua Kellogg reports financial support was provided by National Institute of Food and Agriculture. Gary Perdew reports financial support was provided by National Institute of General Medical Sciences. Gary Perdew reports financial support was provided by National Institute of Environmental Health Sciences. Andrew Patterson reports financial support was provided by National Institute of Environmental Health Sciences."

"This work was supported in part by the USDA National Institute of Food and Agriculture’s Hatch Appropriations (PEN04772), by NIH’s National Institute of General Medical Sciences (T32GM108563), and by NIEHS R35 ES028244 (GHP), ES028288 (ADP). The authors would like to thank the Huck Institute’s Metabolomics Core Facility, and Dr. Tapas Mal of the Nuclear Magnetic Resonance Facility at the Pennsylvania State University for supporting instrumentation and data collection. CRediT authorship contribution statement: Xiaoling Chen: Conceptualization, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing. Andrew D. Patterson: Conceptualization, Resources, Writing – review & editing. Gary H. Perdew: Conceptualization, Resources, Writing – review & editing. Iain A. Murray: Investigation, Resources, Writing – review & editing. Joshua J. Kellogg: Conceptualization, Investigation, Data curation, Writing – original draft, Writing – review & editing, Visualization, Supervision, Project administration, Funding acquisition."