Dyskerin and telomerase RNA component are sex-differentially associated with outcomes and Sunitinib response in patients with clear cell renal cell carcinoma.

"the rna sequencing data from 10 ccrcc patients were deposited in the geo database (gse217386). availability of data and materials source data downloaded from public databases are provided with this paper. data from the immotion150 and151 trial were downloaded from european genome-phenome archive (ega) under accession number egas00001002928"

"Declarations Ethics approval and consent to participateThe study was approved by the Institutional review board of Qilu Hospital of Shandong University (#KYLL-2021(KS)-192) and the signed informed consent was obtained from all patients. Research work was carried out in accordance with the Helsinki Declaration. Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

"Funding Open access funding provided by Karolinska Institute. This work was supported by grants from Scientific Research Foundation of Qilu Hospital of Shandong University (Qingdao) (No. QDKY2019QN17), National Natural Science Foundation of China (No. 82103557, 82002674 and 81972475), Shandong Provincial Natural Science Foundation (No. ZR2020QH245), the Swedish Cancer Society (No. 22 1989 Pj), the Cancer Society in Stockholm (201393), and Karolinska Institute and Karolinska Institute Foundation (2022-01889)."