Bruton's tyrosine kinase inhibition reduces disease severity in a model of secondary progressive autoimmune demyelination.

Authors:
Evonuk KS; Wang S; Mattie J; Cracchiolo CJ; Mager R and 14 more

Journal:
Acta Neuropathol Commun

Publication Year: 2023

DOI:
10.1186/s40478-023-01614-w

PMCID:
PMC10337138

PMID:
37438842

View on PubMed View on PMC View Publisher
Journal Information

Full Title: Acta Neuropathol Commun

Abbreviation: Acta Neuropathol Commun

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Neurology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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Transparency Score
3/6
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Evidence found in paper:

"Declarations Ethics approval and consent to participateAnimal studies were performed under the protocols approved by the Institutional Animal Care and Use Committees at Hooke Laboratories and Explora BioLabs, and in accordance with National Institutes of Health animal use guidelines. Consent for publicationNot applicable. Competing interestsIY, WP, ZN, and LC are employees and stockholders of Gossamer Bio. Competing interests IY, WP, ZN, and LC are employees and stockholders of Gossamer Bio."

Evidence found in paper:

"Funding All work described in this report was funded by Hooke Laboratories and Gossamer Bio."

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Paper is freely available to read
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Last Updated: Aug 05, 2025