A method for polyclonal antigen-specific T cell-targeted genome editing (TarGET) for adoptive cell transfer applications.

"the raw and processed scrna-seq data generated in this study will be deposited in the gene expression omnibus under accession number gse234778 ."

"Declaration of interests The authors declare no competing interests."

"We thank the Genomics Facility Basel and FACS Core facility of the Department of Biomedicine, University Hospital of Basel, for excellent support and assistance throughout this study. Acknowledgments go to the blood donors, and to Dr. Glenn Bantug for providing the EBV strain. This work was supported by the Swiss National Foundation Grant 32003B_204944 (to N.K.), NCCR Antiresist Grant No. 180541, Switzerland (to N.K.), Bangerter–Rhyner Stiftung (to N.K.), 10.13039/501100003006ETH Zurich Post-doctoral Fellowship, Switzerland (to R.B.D.R.), 10.13039/501100013850Helmut Horten Stiftung, Switzerland (to S.T.R.), and NCCR Molecular Systems Engineering, Switzerland (to S.T.R.)."