Presymptomatic and early pathological features of MAPT-associated frontotemporal lobar degeneration.

"Declarations Ethics approval The data presented in this article utilized human tissue that was procured via the Netherlands Brain Bank. The protocol of the Netherlands Brain Bank is in accordance with the ethical standards of our institution and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Approval from an ethical committee was not required and all study procedures were performed in accordance with local ethical regulations. Informed Consent Informed consent for brain donation and use for scientific research was obtained from all patients included in this study prior to death. Competing interestsThe authors report no competing interests. Competing interests The authors report no competing interests."

"Funding This study was supported by two Memorabel grants from Deltaplan Dementie (The Netherlands Organisation for Health Research and Development; grant numbers 733050103 and 733050513), Alzheimer Nederland and the Bluefield Project to Cure Frontotemporal Dementia."