Functional ProTracer identifies patterns of cell proliferation in tissues and underlying regulatory mechanisms.

"Competing interests The authors declare no competing interests."

"This work was supported by National Science Foundation of China (82088101, 32050087, 32100592, 32170848, 32100585, and 32100648), National Key Research & Development Program of China (2019YFA0802000, 2019YFA0110403, and 2022YFA104200), CAS Project for Young Scientists in Basic Research (YSBR-012), Youth Innovation Promotion Association CAS, Shanghai Pilot Program for Basic Research—CAS, Shanghai Branch (JCYJ-SHFY-2021-0), the Program for Guangdong Introduction Innovative and Entrepreneurial Teams (2017ZT07S347), New Cornerstone Science Foundation through the New Cornerstone Investigator Program and the XPLORER PRIZE, Shanghai Municipal Science and Technology Major Project. We also thank the Shanghai Model Organisms Center, Inc. (SMOC) for mouse generation; and all members of institutional animal facilities for mice husbandry, and cell platform in Center for Excellence in Molecular Cell Science (CEMCS) for help in microscope."