The NuroSleeve, a user-centered 3D printed hybrid orthosis for individuals with upper extremity impairment.

"Declarations Ethics approval and consent to participateThis study has been approved by the Institutional Review Board at Thomas Jefferson University. All participants provided written informed consent before participating. Consent for publicationNot applicable. Competing interestsM.D.S., A.N., and M.A. are inventors on a US provisional patent application that has been filed by Thomas Jefferson University on the methods described in this paper. All other authors report that they do not have any conflicts of interest with the research described. Competing interests M.D.S., A.N., and M.A. are inventors on a US provisional patent application that has been filed by Thomas Jefferson University on the methods described in this paper. All other authors report that they do not have any conflicts of interest with the research described."

"Funding This research was supported by philanthropy to the Farber Institute of Neuroscience at Thomas Jefferson University."

"Trial Registration: ClinicalTrials.gov identifier: NCT04798378, https://clinicaltrials.gov/ct2/show/NCT04798378 , date of registration: March 15, 2021."