Patient and Caregiver Perceptions of Airway Clearance Methods Used for Cystic Fibrosis.

"to understand which factors potentially influence patient attitudes about airway clearance a multivariable regression analysis was performed to determine whether age sex or cftr modulator use were associated with the perceived importance of airway clearance (supplemental data 1 ).; in contrast to other methods of airway clearance the perceived importance of exercise was rated highly regardless of age sex or cftr modulator use (see supplemental data 2 ).; we found that the responses of patients and parents were similar for each type of treatment (supplemental data 3 ).; however 19% of respondents reported spending less than 30 minutes per day (supplemental data 3 ).; supplementary materials supplementary materials supplemental data 1.; supplemental data 2.; supplemental data 3."

"Disclosure A preliminary version of this paper was published as a preprint in Authorea [35]. Conflicts of Interest Dr. Singh is now an employee of Johnson & Johnson. Dr. Singh's spouse is now an employee of Vertex Pharmaceuticals. Dr. Larson Ode has received an honorarium from Vertex Pharmaceuticals for participating in an advisory panel. Dr. Fischer and Dr. Larson Ode have received grant funding from the Cystic Fibrosis Foundation."

"We thank patients and families from the University of Iowa Cystic Fibrosis Center for participating in this study. Cystic Fibrosis Foundation Research and Development Program (STOLTZ19R0, PI: David Stoltz). Salary support is provided in part by start-up funds provided by the Stead Family Department of Pediatrics at the University of Iowa. Clinical research support is funded through P30-DK054759-23 (PI: John Engelhardt). Data storage on REDCap is supported by NIH and the University of Iowa CTSA grant no. UL1TR002537. Open Access funding is enabled and organized by BTAA 2023."