Broad-spectrum neuroprotection exerted by DDD-028 in a mouse model of chemotherapy-induced neuropathy.

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"The authors are grateful to Prof. Angelo Schenone and Dr. Lucilla Nobbio from the Department of Neurosciences, Rehabilitation, Ophthalmology, Genetic ,and Maternal and Infantile Sciences (DINOGMI) (University of Genova, Genova, Italy) and from the Clinica Neurologica of IRCCS Ospedale Policlinico San Martino (Genova, Italy) and to Dr. Donatello Carrino from the Department of Experimental and Clinical Medicine (University of Florence, Florence, Italy) for their practical and theoretical support in histopathological analysis. This research was funded by the Italian Ministry of Instruction, University and Research (MIUR), and by Daya CNS, LLC. The authors declare no conflicts of interest. Parthasarathi Rajagopalan is the inventor of DDD-028 and Daya CNS, LLC is the patent owner. Conceptualization: Raghavan Rajagopalan, Parthasarathi Rajagopalan, and Lorenzo Di Cesare Mannelli; Methodology: Elena Lucarini and Massimo Leandri; Software: Elena Lucarini and Jacopo J.V. Branca; Validation: Laura Micheli and Massimo Leandri; Formal analysis: Elena Lucarini, Clara Ciampi, and Jacopo J. V. Branca; Investigation: Elena Lucarini and Clara Ciampi; Resources: Carla Ghelardini and Alessandra Pacini; Data Curation: Elena Lucarini and Laura Micheli; Writing—Original Draft: Elena Lucarini and Laura Micheli; Writing—Review and Editing: Massimo Leandri, Raghavan Rajagopalan, and Alessandra Pacini; Visualization: Elena Lucarini and Lorenzo Di Cesare Mannelli; Supervision: Carla Ghelardini and Parthasarathi Rajagopalan; Project administration: Raghavan Rajagopalan and Lorenzo di Cesare Mannelli; Funding acquisition: Carla Ghelardini and Lorenzo Di Cesare Mannelli.The data sets generated during or analysed during the current study are available from the corresponding author on reasonable request."