High Frequency of Antiviral Resistance Mutations in HBV Genotypes A2 and H: Multidrug Resistance Strains in Mexico.

"accession numbers submitted to genbank of the hbv samples identified in this study appear as mf150686 mf150687 mk568525 mk568530 mk568531 mk568535 mn818843 mn818844 for genotype a2; mf150685 was subgenotype d4; mf150688 mf150689 mf150690 mf150693 mf150694 were subgenotype f1b; mk568529 mk568536 mn818845 mn818846 mn818847 were genotype g; mf150691 mf150692 mf150695 mf150696 mk568522 mk568523 mk568524 mk568526 mk568527 mk568528 mk568532 mk568533 mk568534 mn818829 mn818842 were genotype h for highly divergent sequences from their classification cluster a recombinant analysis was carried out using three tools genbank genotyping tool ( https://www ncbi nlm nih gov/projects/genotyping/formpage cgi ) jumping profile hidden markov model ( http://jphmm gobics de/jphmm html ) and hbv phylogenetic typing tool version 2 58 ( https://www genomedetective com/app/typingtool/hbv/ ).; according to the information available in the genbank genotype e (kt192626 1) was probably introduced to mexico in 2011 by an african immigrant with chronic hepatitis b."

"The authors have no conflict of interests related to this publication."

"We thank Ali Sebastian Meza-Vazquez, Mariela Guadalupe Macedo-Montero, and Rosa Magaly Gomez-Gutierrez for their technical support. AJ-A was supported by a CONACYT Doctoral Scholarship 2013–2017 to perform this work. This research was funded in part by Consejo Nacional de Ciencia y Tecnologia (CONACYT), grant number PN-2017-5254 to AP, FOSSIS-S0008-2010-1-08-139085 to SR, and the Programa de Apoyo a la Incorporación de NPTC. No. UDG-PTC-1439 to AJ-A."